Databases

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(NIH/NCIF) - Access restricted to NIH & NCI-Frederick sites   |   (NCIF) - Access restricted to NCI-Frederick

A

• AccessScience - McGraw-Hill Encyclopedia of Science and Technology Online and The McGraw-Hill Dictionary. Click on "Subscriber Log-in." (NIH/NCIF)

• AGRICOLA - (1970 - ). via the NIH Ovid gateway, this National Agricultural Library (NAL) database contains bibliographic records of materials acquired by the NAL and cooperating institutions in agricultural and related sciences. Records come from the NAL Online Catalog and NAL's Article Citation Database. (NIH/NCIF)

B

• Biobase Knowledge Library (BKL) - formerly Proteome BioKnowledge Library, this new systems tool includes a new version of the analysis tool, ExPlain. BKL is installed on the Helix Systems at NIH. It is a powerful, web-based collection of gene-regulation oriented scientific databases including Transfac, Transpath, and some Proteome databases (HumanPSD, YPD, WormPD). The ExPlain analysis took can use data in BKL to create a biological interpretation of microarray, proteomic, and ChIP-chip data, and more. Note: Access to these resources will require your NIH domain username and password. Tutorials for using the tools are also available on the CIT website. (NIH/NCIF)

• bioDBnet - developed at the Advanced Biomedical Computing Center (ABCC), SAIC-Frederick, bioDBnet integrates many public databases such as Ensembl, NCBI-Gene, GO, UniProt, Affy, etc. It has tools to get detailed annotation reports and also to convert between biological identifiers like proteins to genes or pathways to genes or RefSeq proteins to Ensembl proteins, etc. Any questions or requests to bioDBnet can be made through the ABCC contact form.

• Biological Abstracts via ISI - (1990 - ). Biological Abstracts, a bibliographic database that emphasizes basic life sciences, is available via ISI Web of Knowledge. Search options include Topic, Source Publication, Taxonomic Data, and CAS Registry Number. Results may be emailed, saved, exported to reference software, or analyzed by author, major concept, super taxa, and other criteria. Thomson Scientific provides an online Biological Abstracts Tutorial describing how to search the database. A link to the Tutorial appears at the bottom of the search screen. For further assistance with searching, see Searching BIOSIS on the ISI Web of Knowledge or contact the Library at NCIFredLibrary@mail.nih.gov. Please Logoff after each session. (NIH/NCIF)

• Britannica Online | About : Encyclopedia Britannica Online. (NIH/NCIF)

C

• Chemical Databases - Information about access to Chemical Abstracts on CD-ROM, Beilstein, and DiscoveryGate in the Scientific Library. (NCIF)

• ChemID Plus - From TOXNET, NLM's Toxicology Data Network, a searchable dictionary of over 370,000 chemicals (names, synonyms, and structures). Includes links to NLM and other databases and resources.

• ChemNavigator - Available to all NIH affiliated scientific researchers, NIH has made an agreement with ChemNavigator to provide a current and comprehensive database of commercially accessible drug discovery screening compounds. If you are an NIH researcher, once you register in the system, you'll have full access to the iResearch System. Then you will be able to perform chemical structure searches for compound samples of interest and purchase these samples through this on-line system. (NCIF/NIH)

• CINAHL Plus - (1982 - ). If not taken directly, click on EbscoHost Research Databases link to search the Cumulative Index to Nursing and Allied Health Literature (CINAHL Plus) database, indexing over 3,200 journals with access to evidence-based care sheets, quick lessons, research instruments, and continuing education modules. (NIH/NCIF)

• Clinical Reader - free, beta interactive resource for browsing clinical, scientific and health literature; updated every 30 minutes, features latest articles from high impact factor & popular journals, health news sources & multimedia content.

• ClinicalTrials.gov - (1982 - ). With over 70,000 trials in 167 countries, this database, a service of the NIH, is a registry of federally and privately supported clinical trials conducted in the United States and around the world. Find trials for a specific medical condition or other criteria in the registry.

• Cochrane Library | About - The Cochrane Collaboration, an international non-profit and independent organisation, produces and disseminates systematic reviews of healthcare interventions, promoting the search for evidence in the form of clinical trials and other studies of interventions. The Cochrane Database of Systematic Reviews is published quarterly as part of The Cochrane Library. Reviewers are health care professionals who volunteer to work in a Collaborative Review Group, with editorial teams overseeing and applying rigorous quality standards to the reviews, . (NIH/NCIF)

• Cold Spring Harbor Protocols - over 700 methods in molecular and cell biology. Free individual registration is required prior to your first use. Login with your personal username and password for each future use. For more protocols, see also Springer Protocols, Methods in Enzymology and the Current Protocols series. (NIH/NCIF)

• Community of Science (COS) Expertise® Database | About - provides detailed professional information including affiliation, area of expertise, publications, and contact information for over 480,000 researchers worldwide. COS registration is required for use. From the menu bar at the top of the COS main page, click on "Join," then the "Join" button on the following page. Type in required information, being sure to select "National Institutes of Health (NIH)" as your institution, then "Continue". (NIH/NCIF)

• Community of Science (COS) Funding Opportunities - database of funding opportunities with over 25,000 records; sponsors from private foundations, public agencies, national and local governments, corporations and more. (NIH/NCIF)

• Conference Papers Index - provides citations [not full text] to papers and poster sessions presented at major scientific meetings. Updated bimonthly, coverage is from 1982. Since 1995, subject emphasis has been in the life sciences, environmental sciences, and aquatic sciences; older material also covers physics, engineering and materials science. (NIH/NCIF)

• Current Index to Statistics | About - indexes publications in statistics and related fields. (NIH/NCIF)

• Cytoscape (software) - an open source bioinformatics software platform for visualizing molecular interaction networks and integrating these interactions with gene expression profiles and other state data. This free software needs to be downloaded on individual computers. (See more detailed description on Library Orientation & Instructional Classes list.)

D

• DailyMed - A public service from NLM, provides information about marketed drugs including FDA approved labels (package inserts).

• DATA.gov - provides free public access to machine readable datasets generated by the Executive Branch of the Federal Government; includes access to searchable data catalogs - the "raw" data catalog, the tool catalog, and the geodata catalog.

• DAVID - Database for Annotation, Visualization, & Integrated Discovery - a web-based bioinformatics resource developed by the NCI-F Laboratory of Immunopathogenesis & Bioinformatics, DAVID provides a comprehensive set of functional annotation tools for investigators to understand biological meaning behind large lists of genes. Read about DAVID.

• DXplain - Diagnostic Decision Support (DXplain) is a decision support system using clinical findings (signs, symptoms, labs) to produce a ranked list of diagnoses. For each diagnosis, it provides justification for consideration, further clinical data to collect, and atypical findings. DXplain doesn't offer definitive medical consultation and should not be used as a substitute for physician diagnostic decision making. (NIH/NCIF)

E

• EcoSal - continually updated Web resource based on ASM Press's Escherichia coli and Salmonella: Cellular and Molecular Biology. (NIH/NCIF)

• EFacts Drug Database - online reference Facts & Comparisons, with drug information, interactions, herbal information, and patient medication handouts. [Click on 'eFacts login page link' if your session has timed out]. (NIH/NCIF).

• EMBASE - searchable drug-related information. Indexes over 4,500 biomedical journals from 70 countries. EMBASE: dated from 1974 to present, with a some records from earlier years. MEDLINE: covers 1966 to present with somerecords from earlier years. Note: to include records from earlier years than 1966 in your search, select as starting year the option: <1966. See PubMed for complete access to MEDLINE. (NIH/NCIF).

F

• Faculty of 1000 Biology | About - online research service that highlights and reviews interesting papers in the life sciences, based on recommendations of over 2300 selected researchers. (NIH/NCIF).

G

• GeneGo, MetaCore, MetaRodent - The CCR Office of Science and Technology Partnerships (OSTP) and the Center for Biomedical Informatics and Information Technology (CBIIT) has formed an agreement with GeneGo, Inc., to provide their pathway analysis database and analysis tools, MetaCoreTM and MetaRodentTM. As an NCI researcher, you have full access to use the MetaCore/MetaRodent platform. Please contact David Goldstein (goldsted@mail.nih.gov, 301-496-4347) or Shoshana Segal (shosh@nih.gov, 301-496-0923) for login and password information. (NIH/NCIF)

• Gene2MeSH - an automated literature-based genome annotation using MeSH.

H

• Health and Psychosocial instruments (HAPI) - (1985 - ). via the NIH Ovid gateway, provides access to information on measurement instruments (questionaires, checklists, interview schedules, index measures, coding schemes, manuals, etc.,) in the health fields, psychosocial sciences, and organizational behavior. (NIH/NCIF)

• Henry Stewart Talks Collection - Biomedical & Life Sciences: this series of specially prepared animated audiovisual presentations with synchronized narration by world leading scientists is keeping researchers informed throughout the world. The collection is constantly being expanded and updated and already over seven hundred leading world experts have recorded presentations especially for Henry Stewart Talks . (NCIF)

• HIV Databases - These databases contain data on HIV genetic sequences, immunological epitopes, drug resistance-associated mutations, and vaccine trials. Also included is access to a large number of tools that can be used to analyze these data. This project is funded by the Division of AIDS of the National Institute of Allergy and Infectious Diseases (NIAID), a part of the National Institutes of Health (NIH).

J

• Journal Citation Reports (JCR) - via ISI's Web of Knowledge interface provides "Impact Factors" & "Journal Rankings," to help evaluate scholarly journals, using citation data from over 8,400 journals. (NCIF)

K

• Kirk-Othmer Encyclopedia of Chemical Technology - Click on 'Article Titles A-Z' or 'Topics' under 'Browse this title' on right side of screen. Includes articles on chemical substances, with their properties, manufacturing, and uses; also focuses on industrial processes and unit operations in chemical engineering, and environmental issues concerning chemical biology. (NIH/NCIF)

L

• LCC Nitric Oxide Database - Learn about Nitric Oxide Research in the Laboratory of Comparative Carcinogenesis, NCI-Frederick, Chemistry Section, using this searchable Nitric Oxide Diazeniumdiolate (or NONOates) Reagents Database.

M

• MedlinePlus | About - Free to all, a consumer health information service of the National Library of Medicine and the National Institutes of Health.

• MiMI (Michigan Molecular Interactions Database) - a database of protein interactions, pathways, and genes.

• MiSearch - a literature search tool that works with NCBI Entrez and displays results in order of those most relevant to your research interests.

• Molecular Imaging and Contrast Agent Database| - free resource for in vivo molecular imaging agents established as a key component of the 'Molecular Libraries and Imaging" program of the NIH Roadmap, a set of inter-agency initiatives accelerating medical research.

N

• Natural Medicines Comprehensive Database - updated daily, searchable by ingredient, name; covers herbal medicines, supplements, vitamins, minerals, & natural medicine. (NIH/NCIF)

• Natural Standard - founded by clinicians and researchers to provide high quality, evidence-based information about complementary and alternative therapies, this international multidisciplinary collaboration now includes contributors from more than 100 eminent academic institutions. (NIH/NCIF)

• NCBI BioSystems Database - biological pathways databases which can be searched directly or accessed via links from Entrez Gene, Protein, PubChem Compound, and more.

• NCI Statistical Tools and Data - for use in statistical cancer research.

• NCI-Frederick-in-Print - this database is a collection of citations for journal articles authored by employees and contractors of the National Cancer Institute at Frederick from 1997 through the present. Please bear in mind that this new product is a work in progress, and we welcome any comments you may have. (NCIF)

• NIH OVID Databases - inlcudes AGRICOLA, Books@Ovid, Health & Psychosocial Instruments, PsychINFO and more. Click "Connect to the Ovid Databases." [Click 'Start Ovid' without user id or password if prompted.] Logoff after each session. (NIH/NCIF)

• NIH RePORTER - beta version of the replacement for the NIH grants database, formerly known as CRISP, includes dollar amounts, the study section that reviewed the grant, and links to patents and papers. (NIH/NCIF)

• NLM Gateway - allows simultaneous searching in multiple retrieval systems at the U.S. National Library of Medicine (NLM). (NIH/NCIF)

O

• OpenHelix - OpenHelix announced the launch of a new portal that assists researchers in conducting breakthrough research. The portal, available to NIH/NCIF employees, directs scientists to the most relevant publicly available bioinformatics and genomics resources on the web, and then gives them immediate access to tutorials, training materials, and useful tips and information developed by OpenHelix. Access requires a one-time individual registration. Read more about OpenHelix. (NIH/NCIF)

• Organohalogen Compounds Database - archives short papers presented at annual Dioxin Symposia from 1990 to date. Sponsored by the nonprofit group, Dioxin 20XX, of the International Advisory Board of the International Symposium of Halogenated Persistent Organic Pollutants (POPs), this free database includes scientific papers in pdf format and covers POPs as they relate to disciplines such as molecular biology, human health risk assessment, management risk assessment, and environmental and analytical chemistry.

P

• Proceedings Resource - InterDok - searchable life sciences-related directory of published proceedings (DoPP) of conferences, symposia, meetings.

• Protein Lounge - systems biology resource - a collection of interactive web-based databases and tools to help life scientists assess and analyze gene-protein data. (NIH/NCIF)

• Protocols Resources - Cold Spring Harbor Protocols | Current Protocols | Methods in Enzymology | Springer Protocols

• PsychInfo - (1806 - ) via the NIH Ovid gateway, provides citations with abstracts to the scholarly literature in the psychological, social, behavioral, and health sciences. (NIH/NCIF)

• PubChem - PubChem provides information on the biological activities of small molecules. It is a component of NIH's Molecular Libraries Roadmap Initiative.

• PubMed @ NCIF | FAQ - Use the 'PubMed @ NCIF' link to view the Scientific Library's 'Full-Text' and 'Print' icons while searching PubMed. PubMed is a free version of MEDLINE with access to an index of biomedical literature journals from 1950 forward, as well as a growing collection of free reference books [NCBI Bookshelf] that can be searched by keyword within the PubMed interface.

Q

• QUOSA Information Manager - QUOSA Information Manager for biomedical researchers enables you to search certain databases, e.g. OVID, and retrieve all full-text articles at one time. Software is designed for individual desktops. Click on the "Download" link on the left side of the QUOSA main page; then download either Windows or Mac Subscriber Version; demos are available on the QUOSA page. Questions about the software or problems with access should be directed to support@quosa.com.
  
  QUOSA archived videocast presentations: November 14, 2007 (http://videocast.nih.gov/launch.asp?14151); and September 13, 2006 (http://videocast.nih.gov/launch.asp?13360). The QUOSA software is available through the institutional license purchased by NCI. (NCI/NCIF)

S

• Science Citation Index Expanded & Social Sciences Citation Index - (also known as Web of Science); see Web of Knowledge below for description. (NIH/NCIF)

• ScienceDirect Database - link to the main page of ScienceDirect's electronic collection of full-text science, technology, medical journals and books and bibliographic information; you can also find a wide variety of other features and content. (NIH/NCIF)

• SCOPUS - an abstract and indexing database from Elsevier Science, Scopus, offers access to over 14,000 peer-reviewed titles from more than 4,000 international publishers covering scientific, technical, medical, and social science literature and 15 million patents. In Scopus, you can set up an email alert to let you know each time a particular article of interest is cited in Scopus. (NIH/NCIF)

• Springer Protocols - full-text access to over 16,000 online biomedical research protocols from Methods in Molecular Biology (1984-), Methods in Molecular Medicine (1996-), content found in Neuromethods, Methods in Pharmacology and Toxicology, and Methods in Biotechnology. Access individual titles in Springer Protocols from the Online Catalog using either the Series title or the unique volume title. (NIH/NCIF)

• Stem Cell Information - the NIH Library's Stem Cell Literature Database. (NIH/NCIF)

• Structural Genomics KnowledgeBase - The Structural Genomics Knowledgebase (SGKB) is a free, comprehensive resource produced in a collaboration between the Protein Structure Initiative (PSI) and Nature Publishing Group (NPG). The site offers you an easy way of keeping abreast of developments both by the PSI and more generally in the fields of structural genomics and structural biology.

T

• TOXMAP (Environmental Health E-Maps) - TOXMAP is a Geographic Information System (GIS) from the Division of Specialized Information Services of the National Library of Medicine that uses maps of the United States to help users visually explore data from the US Environmental Protection Agency (EPA)'s Toxics Release Inventory (TRI) and Superfund Program.

• ToxNet - from NLM, databases on toxicology, hazardous chemicals, environmental health, and toxic releases.

U

• UpToDate - an evidence-based tool for answering clinical questions and identifying treatments with over 75,000 pages of peer-reviewed text, written and reviewed by clinicians. (NIH/NCIF)

W

• Web of Knowledge (WOK) - in March 2007, access to Web of Science was transferred from the NIH intranet to the Thomson ISI commercial server. As part of this migration, all Porpoise Alerts had to be converted to Thomson ISI's Alert Service by April 18, 2007. Learn more about what the Library can do to help you with Alerts.
  
  WOK features a number of online reference products including Web of Science, online version of ISI's Science Citation Index Expanded (1900 - present) & Social Sciences Citation Index, (1956 - present); with "Cited Reference Search," a unique tool for citation reference searching, Journal Citation Reports, for impact factors and citation data for over 8,000 journal titles; ISI HighlyCited.com, to identify highly cited researchers, Biological Abstracts, MEDLINE, BiologyBrowser, and Index to Organism Names. (NIH/NCIF)